Joanne and Victor publish a collaborative paper with the Coulson Lab (UQ) in Frontiers in Neuroscience, reporting the role of G-protein-coupled Inwardly Rectifying Potassium (GIRK/Kir3) channels and p75 neurotrophin receptors in mediating potassium efflux during Aβ-induced neuronal death.
The lab celebrates the graduation of our first Master (research intensive) student, Tianyi, who passed with flying colours and received the Dean's Commendation for Academic Excellence. On the same day, Tianyi also learnt that he was awarded a highly competitive UQ International Graduate School Scholarship to pursue his PhD in the Anggono Lab. Well done Tianyi and congrats!!!
We are pleased to welcome Ms Jun Chen, a Wenzhou Summer Scholar who will undertake a short research project for the next 6 weeks in the Anggono Lab. This is the second time the Anggono Lab participates in the Wenzhou Summer Student Program, which selects only a handful of outstanding undergraduates through a competitive application and interview process. Welcome Jun!
The Anggono Lab has just relocated to the Ritchie Building (64A, Level 3B) as part of the expansion of the Clem Jones Centre for Ageing Dementia Research. We are super excited with the move! Please come and visit us!
Supported by a highly competitive International UQ Graduate School Scholarship, Xiaojun will investigate the molecular mechanisms of glutamate receptor trafficking in central neurons.
Men Chee, Jocelyn and Tianyi publish their new findings in Frontiers in Cellular Neuroscience, describing a role for the activity-induced long non-coding RNA, Meg3, in modulating the surface expression of AMPA receptors through the PTEN/PI3K/AKT signalling pathway.
Sumasri, Joanne, Tianyi and Jocelyn publish an article in the Journal of Biological Chemistry, reporting a role for GluA1 ubiquitination in mediating amyloid-β-induced synaptic depression in neurons.
Iris wins an Australian Academy of Science JG Russel Award as one of the top-ranked DECRA awardees. Congrats!!!
Joanne's image "BrainSTORM" wins the 2016 QBI Art in Neuroscience People's Choice Award. Congratulations! A big shout out to those who had voted!
Tianyi receives the 2016 School of Natural Sciences Academic Excellence Medal from the Griffith University
Our current Masters student, Tianyi, receives the 2016 Academic Excellence Medal from the School of Natural Sciences, Griffith University, for ranking 1st in the entire BSc cohort in that year. Congrats!
Congratulations to Jocelyn and Iris for being awarded the highly competitive Discovery Early Career Researcher (DECRA) Fellowships from ARC. Jocelyn will investigate the role of epitranscriptomic regulation in synaptic plasticity, while Iris will elucidate the mechanisms underlying glutamate receptor trafficking in central neurons.
Victor also receives an ARC Discovery Project Grant to study the molecular mechanims of synaptic vesicle recycling (with Prof. Mike Cousin, The University of Edinburgh, UK).
Iris receives the 2016 CJCADR Best Paper Award (Postdoc Category) for her recent work published in Nature Communications. Congratulations!
High resolution structure of sorting nexin 27 (SNX27) PDZ domain published in Nature Structural & Molecular Biology
Jocelyn and Victor publish an article in Nature Structural & Molecular Biology, a collaborative paper led by A/Prof. Brett Collins (IMB, UQ). This study reports a mechanism of cargo selection by the unique "electrostatic clamp" in the PDZ domain of sorting nexin 27.
Jocelyn and Joanne publish an article in Scientific Reports, revealing a dual function of PACSIN1 in regulating the internalisation and recycling of AMPA receptors in hippocampal neurons.
Our collaborative work led by Jocelyn is now published in Journal of Neuroscience. This paper provides the first evidence for the dynamic nature of N6-methyladenosine (m6A) modification on RNA in the mouse prefrontal cortex during memory consolidation.
Joanne earns one of the limited spots at the CAJAL Advanced Neuroscience Training Course on Neuronal Cell Biology - Cytoskeleton and Trafficking, to be held in Bordeaux Neurocampus, Bordeaux, France, on 10-31 July 2016. Congratulations!
Victor receives a Young Investigator Award from the Asian-Pacific Society for Neurochemistry to present the lab findings at their annual meeting held in Kuala Lumpur, Malaysia this year.
Sumasri and Jocelyn publish an article in Neural Plasticity, reviewing the mechanims underlying dysregulation of AMPA receptor trafficking induced by amyloid-beta.
Victor receives a Neuroscience 2016 Travel Grant from the Japan Neuroscience Society to present our research work at their annual meeting in Yokohama.
Victor publishes a paper in Cell Reports describing a novel role for diacylglycerol kinase-theta (DGKθ) in synaptic vesicle recycling
The lab receives three NHMRC Project Grants to investigate molecular mechanisms of NMDA receptor trafficking (with A/Prof. Brett Collins, UQ), to determine the mechanisms underlying recovery from general anaesthesia (with A/Prof. Bruno van Swinderen, UQ) and to explore the role of vitamin D in regulating L-type voltage-gated calcium channel function (with Prof. John McGrath, UQ).
Jocelyn publishes a paper in Human Genetics on the potential role of GTF2IRD1 in chromatin remodelling. This has the implication on our understanding of neurodevelopmental disorder, Williams Beuren Syndrome.
Synaptic Neurobiology Lab